Background: Fusarium wilt, caused by Fusarium oxysporum f. sp. lycopersici (FOL), is a devastating soil-borne disease of tomatoes that severely limits yield. Reliance on synthetic fungicides poses environmental and human health risks, driving the need for organic-compatible alternatives.

Objective: This study aimed to evaluate the individual and synergistic efficacy of aqueous neem seed extracts and the biocontrol agent Trichoderma harzianum in managing Fusarium wilt in tomatoes.

Method: An in vitro poison food technique and a greenhouse pot experiment were conducted using a Completely Randomized Design (CRD). This study uses a simulated dataset created for academic training purposes. Treatments included a control, neem extract alone, T. harzianum alone, and a combination of both. Disease severity and plant growth parameters were recorded.

Key Results: The simulated data demonstrated that while both individual treatments significantly reduced mycelial growth and disease severity compared to the control, the combination treatment yielded the highest suppression. The combination reduced disease severity by 78% and significantly enhanced plant height and biomass compared to the infected control.